Abstract S37
| WT | p55 KO | p75KO | DKO | |
|---|---|---|---|---|
| Results shown as mean (SD); n = 4–11/observation. | ||||
| *p<0.01 v wildtype (WT). | ||||
| Final PIP (cmH2O) | 55.5 (2) | 46.6 (2)* | 62.6 (3)* | 58.5 (5) |
| Final pO2 (mmHg) | 304 (44) | 391 (27)* | 287 (41) | 328 (75) |
| Lavage fluid protein (mg/ml) | 5.7 (0.9) | 1.7 (0.6)* | 6.2 (0.5) | 4.8 (2.0) |
| Lung wet:dry weight ratio | 7.9 (0.5) | 5.7 (0.7)* | 7.8 (0.4) | 7.1 (0.9) |
| Survival to 2 hours (%) | 27 | 100 | 0 | 33 |