Clinical diagnosis | n | T SPOT positive, n = 75 (6) | T SPOT negative, n = 63 (14) | TST positive | TST negative |
---|---|---|---|---|---|
The numbers in brackets refer to specimens that were not processed according to the protocol (stored overnight or frozen before testing). | |||||
*Sputum from one patient grew both M avium and M xenopi. | |||||
†This test result was subsequently reviewed by OI and reported as borderline positive. | |||||
‡These patients were aged 31, 33, and 38 years; one was an intravenous drug abuser; one had an isoniazid resistant strain; none had HIV co-infection. | |||||
Microscopy +, TB cultured | 23 | 18 (2) | 1† (2‡) | 1 | 0 |
Microscopy −, TB cultured | 11 | 9 (1) | 0 (1‡) | 5 | 0 |
Microscopy +, culture −, TB Rx | 1 | 0 | 1 | 0 | 0 |
Granulomata on biopsy & TB Rx | 4 | 2 (1) | 1 | 3 | 0 |
Microscopy −, culture −, TB Rx | 16 | 8 | 6 (2) | 5 | 6 |
Microscopy −, culture −, no TB Rx | 54 | 17 (2) | 32 (3) | 2 | 11 |
Atypical mycobacteria* | 6 | 2 | 3 (1) | 0 | 1 |
M gordonae | 1 | 1 | 0 | 0 | 0 |
M avium | 2 | 0 | 2 | 0 | 0 |
M fortuitum | 1 | 0 | 0 (1) | 0 | 1 |
M xenopi | 3 | 1 | 2 | 0 | 0 |
Firm alternative diagnosis | 16 | 2 | 12 (2) | 1 | 3 |
Malignancy | 5 | 1 | 3 (1) | 1 | 1 |
Sarcoidosis | 8 | 1 | 6 (1) | 0 | 2 |
Other | 3 | 0 | 3 | 0 | 0 |
Culture pending/contaminated | 27 | 17 | 7 (3) | 4 | 4 |