Table 2

 Groups based on genotype in CF adult patients

Functional classesGenotypeNo of subjects
I–IG542X/W1282X1
R1162X/1898+3A→G1
R1162X/CFTRdele191
I–IIF508del/G542X5
F508del/711+1G→T2
F508del/1717-8G→A1
F508del/936delTA1
F508del/R1162X1
N1303K/1609delCA1
I–IIIG542X/D1270N+R74W1
711+1G-T/G551D1
I–IVG542X/P205S1
Q890X/R334W1
1609delCA/R347H1
I–VG542X/2789+5G→T2
G542X/1811+1.6kbA→G1
1782delA/2789+5G→A1
1609delCA/1811+1.6kbA→G1
II–IIF508del/F508del21
F508del/N1303K1
F508del/R1066C1
II–IIIF508del/D1270N+R74W1
I507del/D1270N+R74W1
II–IVF508del/L206W4
F508del/R334W3
F508del/R117H3
F08del/R347H2
F508del/D836Y1
II–VF508del/2789+5G→A5
F508del/3849+10kbC→T2
F508del/1811+1.6kbA→G2
F508del/3272+26G→A1
N1303K/1811+1.6kbA→G1
N1303K/2789+5G→A1