Table 3

 Clinical characteristics and histological pattern in patients with chronic bird fancier’s lung (BFL)

Group A: BOOP-like or cellular NSIP-like lesions(N = 7)Group B: fibrotic NSIP-like lesions(N = 8)Group C: UIP-like lesions(N = 11)
BOOP, bronchiolitis obliterans organising pneumonia; NSIP, non-specific interstitial pneumonia; UIP, usual interstitial pneumonia; PDE, pigeon dropping extracts; BDE, budgerigar dropping extracts; VC, vital capacity; Tlco, carbon monoxide lung transfer factor; HRCT, high resolution computed tomography; BAL, bronchoalveolar lavage.
Data are presented as mean (SE) or number or % of positive unless otherwise indicated.
*Data are presented as number or % of positive in seven group A patients with BOOP-like or cellular NSIP-like lesions, in seven group B patients with fibrosing NSIP-like lesions, and in nine group C patients with UIP-like lesions who were treated with steroid.
†p<0.05, group A v group C; ‡p<0.01, group A v group C; §p<0.05, group B v group C; **p<0.01, group A v group B; ††p<0.05, group A v group B.
Age (years)56.9 (4.3)58.4 (1.8)64.7 (2.1)
Cases of recurrent acute episodes (%)85.7‡50.0§0.0‡ §
Exertional dyspnoea (%)85.7100.090.9
Duration of symptoms before surgical lung biopsy (months)19.3 (7.5)46.3 (14.2)24.2 (5.3)
Exposure periods (years)11.6 (2.8)18.0 (2.8)11.0 (2.5)
Finger clubbing (%)0.0‡50.081.8‡
Anti-PDE or BDE antibodies (%)85.7†62.518.2†
Antigen induced lymphocyte proliferation (%)100.087.590.9
VC (% pred)80.2 (9.1)60.6 (5.3)74.8 (7.2)
Tlco (% pred)58.7 (5.8)49.1 (6.0)52.3 (5.7)
Micronodules on HRCT (%)57.1†25.00.0†
Traction bronchiectasis on HRCT (%)28.6** ‡100.0**100.0‡
Honeycombing on HRCT (%)0.0‡50.090.9‡
BAL lymphocytes (%)77.0 (2.6)** ‡40.8 (8.6)** §19.1 (2.9)‡ §
Favourable response to treatment (%)*7/7 (100.0%)** ‡1/7 (14.3%)**1/9 (11.1%)‡
No response to treatment (%)*0/7 (0.0%)† ††5/7 (71.4%)††6/9 (66.7%)†