DNA binding of transcription factors NF-κB and AP-1 in lung biopsy specimens
| Non-smokers | Healthy smokers | Stable COPD | Very severe exacerbations of COPD | |
|---|---|---|---|---|
| Data shown as median (IQR) values. | ||||
| No biopsy specimens were obtained from patients with severe exacerbations of COPD. | ||||
| No significant difference was detected between the groups for either NF-κB or AP-1. | ||||
| NF-κB | 29.7 (22.0–108.7) | 116.3 (64–199.7) | 74.9 (45.9–127.4) | 34.1 (6.7–103.1) |
| (n = 7) | (n = 4) | (n = 3) | (n = 7) | |
| AP-1 | 12.6 (0–40.0) | – | 18.8 (16.5–21.2) | 40.5 (32.6–48.3) |
| (n = 4) | – | (n = 2) | (n = 2) | |