FVC (% of predicted) | | | |

Mean (SD) | 94.3 (14.0) *v* 107.6 (12.1) | 98.6 (15.8) *v* 106.1 (13.5) | 4.3 (1.7) *v* −1.6 (1.0) |

95% CI | 7.9 to 18.7 | 1.5 to 13.5 | −9.6 to −2.1 |

p value | p<0.01* | p = 0.02* | p<0.01* |

FEV_{1} (% of predicted) | | | |

Mean (SD) | 102.0 (13.1) *v* 111.1 (14.7) | 103.8 (12.7) *v* 108.2 (15.4) | 1.8 (1.2) *v* −2.9 (1.3) |

95% CI | 3.0 to 15.1 | −1.8 to 10.6 | −9.0 to −0.4 |

p value | p<0.01* | p = 0.17 | p = 0.03* |

VC (% of predicted) | | | |

Mean (SD) | 94.7 (15.1) *v* 107.9 (12.5) | 98.4 (16.4) *v* 105.0 (17.9) | 3.7 (1.4) *v* −2.8 (1.4) |

95% CI | 7.4 to 18.9 | −0.9 to 14.1 | −11.3 to −1.8 |

p value | p<0.01* | p = 0.08 | p = 0.01* |

TLC (% of predicted) | | | |

Mean (SD) | 94.6 (16.1) *v* 110.3 (16.4) | 98.2 (19.3) *v* 110.1 (14.1) | 3.6 (3.9) *v* −0.2 (1.9) |

95% CI | 8.7 to 22.7 | 4.0 to 19.7 | −11.6 to 4.0 |

p value | p<0.01* | p<0.01* | p = 0.33 |

RV (% of predicted) | | | |

Mean (SD) | 96.7 (39.4) *v* 115.7 (49.7) | 99.9 (51.6) *v* 118.6 (38.5) | 3.2 (12.3) *v* 2.9 (6.2) |

95% CI | −1.2 to 39.2 | −2.4 to 39.7 | −25.0 to 24.3 |

p value | p = 0.06 | p = 0.08 | p = 0.98 |

Tlco (% of predicted) | | | |

Mean (SD) | 84.3 (17.5) *v* 101.4 (13.4) | 87.7 (21.0) *v* 98.3 (16.6) | 3.4 (2.2) *v* −2.9 (1.6) |

95% CI | 10.9 to 23.4 | 3.0 to 18.2 | −11.9 to −0.6 |

p value | p<0.01* | P = 0.01* | p = 0.03* |

Kco (% of predicted) | | | 4.5(1.7) vs 2.6(1.3) |

Mean (SD) | 104.9 (13.5) *v* 107.4 (13.7) | 109.4 (15.3) *v* 110.1 (13.6) | |

95% CI | −3.4 to 8.2 | −5.3 to 6.7 | −6.5 to 2.7 |

p value | p = 0.41 | P = 0.83 | p = 0.42 |

Pimax (% of predicted) | | | |

Mean (SD) | 104.2 (29.1) *v* 108.5 (29.8) | 105.6 (30.6) *v* 105.8 (25.8) | 0.6 (5.6) *v* −2.6 (2.7) |

95% CI | −8.5 to 17.0 | −11.4 to 11.8 | −14.0 to 7.6 |

p value | p = 0.51 | P = 0.97 | p = 0.56 |

Pemax (% of predicted) | | | |

Mean (SD) | 75.7 (14.9) *v* 73.2 (18.9) | 74.5 (19.1) *v* 71.5 (21.4) | −1.8 (2.8) *v* −1.5 (2.1) |

95% CI | −10.2 to 5.2 | −11.9 to 5.8 | −7.1 to 7.6 |

p value | p = 0.52 | P = 0.49 | p = 0.94 |

6MWD (m) | | | |

Mean (SD) | 458.2 (86.8) *v* 466.4 (80.7) | 519.7 (101.4) *v* 491.5 (92.9) | 64.5 (14.5) *v* 25.1 (9.7) |

95% CI | −27.1 to 43.6 | −11.4 to 11.8 | −74.9 to −4.0 |

p value | p = 0.64 | P = 0.97 | p = 0.03* |