Table 2

 Comparison of smokers and non-smokers with asthma: morning peak expiratory flow (PEF) measurements at 2, 6 and 12 weeks after receiving inhaled beclomethasone

Mean (SD) changeAdjusted p value
SmokersNon-smokersAdjusted difference(95% CI)
*n varies because of non-attenders/missing data at visits.
Beclomethasone 400 μg daily
2 weeksn* = 18n = 28
Δ Morning PEF−10 (21)7 (21)−17 (−28 to −5)[unadjusted −17 (−30 to −4)]0.0062[unadjusted 0.011]
6 weeksn = 16n = 28
Δ Morning PEF−11 (43)13 (28)−26 (−46 to −5)[unadjusted−23 (−45 to −2)]0.0146[unadjusted 0.036]
12 weeksn = 16n = 28
Δ Morning PEF−6 (42)19 (29)−25 (−45 to −4)[unadjusted −25 (−46 to −3)]0.0197[unadjusted 0.025]
Beclomethasone 2000 μg daily
2 weeksn = 21n = 23
Δ Morning PEF8 (25)16 (33)−13 (−41 to 16)[unadjusted −8 (−26 to 10)]0.38[unadjusted 0.36]
6 weeksn = 18n = 24
Δ Morning PEF13 (26)19 (29)−19 (−48 to 10)[unadjusted −6 (−23 to 11)]0.19[unadjusted 0.49]
12 weeksn = 20n = 25
Δ Morning PEF11 (31)18 (40)−15 (−50 to 21)[unadjusted −7 (−29 to 15)]0.40[unadjusted 0.50]
Beclomethasone 400 μg and 2000 μg combined results
2 weeksn = 39n = 51
Δ Morning PEF0 (25)11 (27)−12 (−24 to 0)[unadjusted −11 (−23 to 0)]0.058[unadjusted 0.042]
6 weeksn = 34n = 52
Δ Morning PEF2 (37)16 (28)−17 (−32 to −2)[unadjusted −14 (−28 to 0)]0.0238[unadjusted 0.054]
12 weeksn = 36n = 53
Δ Morning PEF3 (37)19 (34)−18 (−35 to −1)[unadjusted −15 (−30 to 0)]0.0346[unadjusted 0.049]