Changes in lung function before and after treatment with etanercept
| Before treatment | After treatment | Mean change from baseline | p value | |
|---|---|---|---|---|
| All values are mean (SE) except *geometric mean (95% CI). | ||||
| †Change shown as doubling dilutions of methacholine. | ||||
| FEV1 (l) | 1.91 (0.5) | 2.16 (0.6) | 0.24 (0.18) | 0.01 |
| FVC (l) | 2.55 (0.2) | 2.88 (0.2) | 0.33 (0.29) | 0.03 |
| Morning PEF (predicted %) | 54.8 (5.6) | 61.0 (5.8) | 5.75 (5.65) | 0.023 |
| Evening PEF (predicted %) | 55.3 (5.1) | 63.9 (5.1) | 8.04 (5.23) | 0.005 |
| Methacholine PC20 (mg/ml)* | 0.21 (0.1 to 0.64) | 1.28 (0.53 to 2.92) | 2.5 (1.75)† | 0.033 |