Comparison of clinical characteristics of patients who died from various causes of mortality and the effect of corticosteroids for these causes of mortality
Respiratory | Cardiovascular | Cancer | Others | |
---|---|---|---|---|
Hazard ratios (HRs) were adjusted for age, sex, baseline post-bronchodilator FEV1, smoking status, body mass index, and individual trial (see Methods section for details). | ||||
FEV1, forced expiratory volume in 1 second; ICS, inhaled corticosteroids. | ||||
Total number of deaths | 69 | 60 | 42 | 30 |
Mean (SD) age (years) | 66.1 (6.6) | 63.5 (7.0) | 63.8 (6.3) | 63.6 (10.6) |
Men | 59 (85.5%) | 50 (83.3%) | 30 (71.4%) | 23 (76.7%) |
Baseline FEV1 (% of predicted) | 39.1 (13.1) | 51.7 (17.1) | 57.8 (17.0) | 50.0 (17.7) |
Adjusted HR (95% CI) for mortality between ICS and placebo groups | 0.80 (0.50 to 1.28) | 0.98 (0.59 to 1.62) | 0.55 (0.29 to 1.03) | 0.57 (0.27 to 1.19) |