Effect of different exercise intensities
| Study (no of patients in each group) | Outcome measure | Difference follow up minus baseline for each group | Difference between groups (95% CI where available) |
|---|---|---|---|
| HIE, high intensity exercise; LIE, low intensity exercise; CE, continuous exercise; IE, interval exercise; SE, standardised exercise; IE, individualised exercise; EE, eccentric exercise; Wmax, maximum exercise capacity; 6MWD, 6 minute walking distance; CWRT, constant work rate test; CRQ, Chronic Respiratory Questionnaire. | |||
| Coppoolse43 (CE n = 11; IE n = 10) | Wmax (Watts) | CE: 8; IE: 13 | −5, p>0.05 |
| Peak oxygen uptake (V˙o2, l/min) | CE: 0.15; IE: 0.07 | 0.08, p>0.05 | |
| Lactate at sub-maximum exercise capacity | CE: −31%; IE: −20% | −11%, p>0.05 | |
| Leg pain at Wmax | CE: −13%; IE: −26% | 13%, p>0.05 | |
| Dyspnoea at Wmax | CE: −2%; IE: −15% | 13%, p>0.05 | |
| Raw data only for the whole study group available but not for each group. Changes within continuous and interval exercise group only in percentages | |||
| Vogiatzis35 (CE n = 18; IE n = 18) | CRQ Dyspnoea (raw data for CRQ scores only from figures available) | CE: 1.7; IE: 1.2 | 0.5 (p>0.05) |
| CRQ Fatigue | CE: 0.6; IE: 0.6 | 0.0 (p>0.05) | |
| CRQ Emotional function | CE: 0.6; IE: 0.4 | 0.2 (p>0.05) | |
| CRQ Mastery | CE: 0.4; IE: 0.4 | 0.0 (p>0.05) | |
| Wmax (Watts) | CE: 13; IE: 14 | −1 (p>0.05) | |
| Dyspnoea at Wmax (VAS) | CE: −3; IE: −4 | 1 (p>0.05) | |
| Peak oxygen uptake (V˙o2, l/min) | CE: 0.13; IE: 0.12 | 0.01 (p>0.05) | |
| Ventilation at peak exercise intensity (l/min) | CE: −3.9; IE: −4.1 | 0.2 (p>0.05) | |
| Lactate threshold (l/min) | CE: 0.12; IE: 0.11 | 0.01 (p>0.05) | |
| Kaelin44 (CE n = 6; IE n = 7) | 6MWD (m) | CE: 39; IE: 80 | 41 (−17 to 99) |
| Rooyackers45 (IE n = 12; IE +EE n = 12) | CRQ Dyspnoea | IE: 1.34; IE +EE: 0.86 | 0.48 (−0.20 to 1.16) |
| CRQ Fatigue | IE: 0.65; IE +EE: 1.0 | −0.35 (−0.74 to 0.04) | |
| CRQ Emotional function | IE: 0.46; IE +EE: 0.59 | −0.13 (−0.67 to 0.41) | |
| CRQ Mastery | IE: 0.60; IE +EE: 1.05 | −0.45 (−0.98 to 0.08) | |
| Wmax (Watts) | IE: 17.0; IE +EE: 10.0 | 7.0 (−3.87 to 17.87) | |
| 6MWD (m) | IE: 123; IE +EE: 118 | 5 (−60 to 70) | |
| Casaburi47 (HIE n = 11; LIE n = 8) | Exercise duration (in minutes) during CWRT at 40% of Wmax | HIE: 2.1; LIE: 1.6 | 0.5 (p>0.05) |
| Exercise duration (minutes) during CWRT at 80% of Wmax | HIE: 4.8; LIE: 0.6 | 4.2 (p<0.05) | |
| Lactate (mEq/l) at Wmax | HIE: −2.7; LIE: −1.0 | −1.7 (p<0.01) | |
| Lactate threshold (l/min) | HIE: 0.18; LIE: 0.08 | 0.1 (p>0.05) | |
| Ventilation Ve (l/min) | HIE: −6.4; LIE: −0.1 | −6.3 (p<0.005) | |
| Vallet48 (SE n = 12; IE n = 12) | Peak oxygen uptake (V˙o2, l/min) | SE: 0.17; IE: 0.31 | −0.14 |
| Anaerobic threshold (ml/kg/min) | SE: 1.2; IE: 3.2 | −2.0 (p<0.05) | |