Table 2

 Median time (95% confidence interval (CI)) in years from onset of symptoms to reaching MRC dyspnoea grades 2–5 and cumulative probability (95% CI) of reaching these end points at 5 and 10 years

End pointnCensoredMedian time (95% CI)5 year probability of reaching end point (95% CI)10 year probability of reaching end point (95% CI)
*Median time not available since fewer than 50% of cases had achieved the end point.
MRC 24775.7 (2.5 to 8.8)0.49 (0.35 to 0.63)0.75 (0.61 to 0.88)
MRC 347159.3 (5.1 to 13.4)0.25 (0.13 to 0.38)0.55 (0.40 to 0.70)
MRC 45232NA*0.19 (0.09 to 0.30)0.31 (0.18 to 0.44)
MRC 55648NA*0.04 (0 to 0.08)0.10 (0.02 to 0.18)
Home oxygen5639NA*0.05 (0 to 0.11)0.23 (0.11 to 0.35)