Significant demographic, clinical, and social risk factors associated with drug resistance in all patients (multivariate analysis)*
| Parameter | Any resistance | Isoniazid | Rifampicin | MDR TB (all cases) | MDR TB (new cases) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| p value | OR(95% CI) | p value | OR(95% CI) | p value | OR(95% CI) | p value | OR(95% CI) | p value | OR(95% CI) | |
| *Parameters are for all TB patients unless indicated for prisoner or civilian subgroups alone. | ||||||||||
| Sex (males v females) in civilians | – | – | 0.036 | 3.0 (1.1 to 8.3) | – | – | – | – | – | – |
| Previous TB treatment for >4 weeks | 0.038 | 1.7 (1.0 to 2.8) | 0.042 | 1.7 (1.1 to 2.8) | – | – | – | – | ||
| Civilians | – | – | 0.001 | 4.0 (2.0 to 8.1) | – | – | 0.001 | 7.4 (1.9 to 29.1) | ||
| Prisoners | – | – | 0.053 | 3.7 (1.1 to 14.2) | – | – | – | – | ||
| Previous treatment at prison dispensary in civilians | – | – | – | – | 0.052 | 4.3 (0.9 to 18.3) | – | – | – | – |
| Currently on TB treatment | 0.002 | 2.5 (1.4 to 5.0) | – | – | 0.029 | 2.2 (1.1 to 4.6) | 0.014 | 2.8 (1.2 to 6.5) | – | – |
| Civilians | 0.004 | 3.7 (1.5 to 9.1) | 0.034 | 2.2 (1.1 to 4.7) | – | – | 0.026 | 4.2 (1.2 to 14.7) | ||
| Currently on long term treatment | – | – | −1.1 | – | 0.051 | 3.4 (1.0 to 11.2) | – | – | – | – |
| Fibrocavitary TB | 0.04 | 5.0 (1.1 to 10.0) | 0.019 | 2.2 (1.1 to 4.4) | 0.001 | 3.5 (1.8 to 6.7) | – | – | – | – |
| Prisoners | 0.005 | 3.4 (1.4 to 8.2) | 0.023 | 3.2 (1.2 to 8.7) | 0.048 | 2.6 (1.1 to 6.9) | ||||
| Accompanying COPD | – | – | 0.042 | 2.1 (1.0 to 4.3) | 0.002 | 3.5 (1.6 to 7.7) | – | – | – | – |
| HIV infection | – | – | – | – | – | – | 0.009 | 0.3 (0.1 to 0.8) | – | – |
| Prisoners | 0.006 | 0.3 (0.1 to 0.7) | ||||||||
| History of imprisonment | – | – | – | – | – | – | 0.021 | 2.1 (1.1 to 4.1) | – | – |
| Civilians | 0.041 | 3.4 (1.1 to 11.1) | ||||||||
| Smoking | – | – | 0.021 | 3.3 (1.2 to 9.2) | – | – | – | – | – | – |
| Recreational drug use | – | – | – | – | – | – | – | – | 0.03 | 3.0 (1.1 to 7.9) |