Predictive potential of severity rules for mortality
| Sensitivity | Specificity | PPV | NPV | Overall accuracy | |
|---|---|---|---|---|---|
| Data are presented as number (%) with 95% confidence intervals (CI). | |||||
| PPV = positive predicted value; NPV = negative predicted value. | |||||
| Modified ATS rule | 44/47 (94%) | 601/647 (93%) | 44/90 (49%) | 601/604 (99.5%) | 645/694 (93%) |
| (82.5 to 98.7) | (90.6 to 94.7) | (38.2 to 59.7) | (98.5 to 99.9) | (90.8 to 94.7) | |
| BTS I | 20/44 (46%) | 534/612 (87%) | 20/98 (20%) | 534/558 (96%) | 554/656 (85%) |
| (30.4 to 61.2) | (84.4 to 89.8) | (12.9 to 29.7) | (93.7 to 97.2) | (81.4 to 87.1) | |
| Original derivation cohort5 | 21/24 (88%) | 322/409 (79%) | 21/108 (19%) | 322/325 (99%) | 343/433 (79%) |
| (67.6 to 97.3) | (74.4 to 82.6) | (12.5 to 28.2) | (97.4 to 99.8) | (75.1 to 83.0) | |
| BTS II | 25/47 (53%) | 537/644 (83%) | 25/132 (19%) | 537/559 (96%) | 562/691 (81%) |
| (38.1 to 67.9) | (80.3 to 86.2) | (12.6 to 26.7) | (94.1 to 97.5) | (78.2 to 84.2) | |
| Original derivation cohort5 | 9/23 (39%) | 386/411 (94%) | 9/34 (27%) | 386/400 (97%) | 395/434 (91%) |
| (19.7 to 61.5) | (91.2 to 96.0) | (12.9 to 44.4) | (94.2 to 98.1) | (87.9 to 93.5) | |
| Modified BTS rule | 21/41 (51%) | 440/551 (80%) | 21/132 (16%) | 440/460 (96%) | 461/592 (78%) |
| (35.1 to 67.1) | (76.3 to 83.1) | (10.1 to 23.3) | (93.4 to 97.3) | (74.3 to 81.2) | |
| Sepsis | 41/46 (89%) | 141/635 (22%) | 41/535 (8%) | 141/146 (97%) | 182/681 (27%) |
| (76.4 to 96.4) | (19.0 to 25.6) | (5.6 to 10.3) | (92.2 to 98.9) | (23.4 to 30.2) | |
| Severe sepsis | 39/44 (89%) | 366/526 (70%) | 39/199 (20%) | 366/371 (99%) | 405/570 (71%) |
| (75.4 to 96.2) | (65.5 to 73.5) | (14.3 to 25.8) | (96.9 to 99.6) | (67.1 to 74.7) | |
| Septic shock | 38/47 (81%) | 630/647 (97%) | 38/55 (69%) | 630/639 (99%) | 668/694 (96%) |
| (66.7 to 90.9) | (95.8 to 98.5) | (55.2 to 0.9) | (97.3 to 99.4) | (94.6 to 97.5) | |