Table 2

 Risk factors for squamous cell carcinoma

Risk factorsUnivariate analysisLogistic regression
Cases (n = 86)Controls (n = 54)OR95% CIp valueOR95% CIp value
*Compared with more peripheral localisation.
FEV1 = forced expiratory volume in 1 second; OR = odds ratio; CI = confidence intervals.
Sex (F/M)9/779/450.780.46 to 2.040.740.920.26 to 2.980.92
Age70.7 (5.8)69.2 (4.5)0.970.93 to 1.110.570.980.94 to 1.040.66
Ex-smokers, n (%)51 (59.4%)34 (63.0%)0.800.57 to 2.490.920.710.45 to 3.160.73
Pack years47.9 (8.7)46.0 (7.6)1.020.99 to 1.020.761.010.99 to 1.020.58
FEV177.2 (2.8)82.7 (4.1)0.980.90 to 1.000.530.990.98 to 1.020.72
Chronic bronchitis, n (%)38 (44.1%)39 (72.2%)0.300.14 to 0.63<0.0010.260.09 to 0.520.001
COPD, n (%)61 (70.9%)23 (42.5%)3.281.61 to 6.70<0.0014.051.93 to 10.570.001
Tumour localisation
Main bronchus, n (%)3 (3.4%)1 (1.8%)4.87*0.43 to 55.3*0.20*5.59*0.38 to 82.6*0.21*
Lobar bronchus, n (%)17 (19.7%)9 (16.6%)3.03*0.93 to 10.1*0.066*2.05*0.57 to 7.70*0.29*
Segmental bronchus, n (%)53 (61.6%)26 (48.1%)3.13*1.22 to 8.99*0.019*2.92*0.98 to 8.68*0.054*
Subsegmental bronchus, n (%)4 (4.6%)6 (11.1%)1.08*0.23 to 5.11*0.92*1.96*0.33 to 11.5*0.47*
More peripheral, n (%)9 (10.4%)12 (22.2%)