Table 2

 Peripheral muscle mass and strength

COPD(n = 29)Healthy subjects(n = 18)Mean difference(95% CI)p value
Values are mean (SE).
MTCSA, mid thigh muscle cross sectional area; MVC, maximal voluntary contraction; MVC/MTCSA, ratio of maximal strength to mid thigh muscle cross sectional area; Tf, time to fatigue.
MTCSA (cm2)66 (3)107 (3)41 (31 to 51)<0.001
MVC (kg)28 (2)45 (3)17 (10 to 23)<0.001
MVC/MTCSA (kg/cm2)0.41 (0.02)0.43 (0.02)0.02 (−0.04 to 0.07)NS
Tf (seconds)42 (3)80 (7)38 (25 to 50)<0.001