COPD patients | Healthy controls | |
---|---|---|
Except where stated, figures are mean (SD) values and between groups compared using unpaired Student’s t test. | ||
Gas exchange and ventilation data on three patients are missing due to equipment failure. | ||
V˙o2peak, peak oxygen uptake; V˙e, ventilation; MVV, maximum voluntary ventilation; RQ, respiratory quotient; HR, heart rate; BS, Borg score; PE, perceived exertion. | ||
*p<0.01, †p<0.05 compared with COPD patients | ||
‡Median (interquartile range); comparison made using Mann-Whitney U test. | ||
Incremental cycle test | ||
Peak work rate (W) | 72 (18.3) | 181 (30.4)* |
V̇o2peak (ml/kg/min) | 15.6 (3.7) | 34.7 (8.1)* |
V˙co2peak (ml/kg/min) | 15.8 (4.1) | 41.2 (10.1)* |
Peak V˙e (l) | 42.4 (11.0) | 77.3 (16.9)* |
Peak V˙e (% MVV) | 106 (33) | 67 (15)* |
Peak RQ | 1.00 (0.07) | 1.19 (0.09)* |
Peak Sao2 (%) | 94.7 (2.3) | 96.6 (1.3)† |
Peak HR (beats/min) | 123 (18) | 130 (22) |
Constant load test | ||
Work rate (W) | 56.7 (15.9) | 143.2 (26.3)* |
End exercise HR (beats/min) | 125 (18) | 135 (15) |
End exercise Sao2 (%) | 91.8 (5.0) | 94.8 (2.0) |
End exercise BS‡ | 5 (2.5) | 3 (3)† |
End exercise PE‡ | 13 (4) | 15 (4.25) |