Table 2

 Reported signs and symptoms of LAM by age group (age at time of survey) and TSC status

Sign/symptomAll respondents(N = 328)Tuberous sclerosis present(N = 51)History of pneumothorax(N = 207)
NA, not applicable.
*p<0.05 across age groups. †p<0.05 between TSC and non-TSC groups. ‡p<0.05 between history of pneumothorax and no history of pneumothorax.
Dyspnoea with exertion73.8*62.8†71.4
Fatigue71.976.270.5
Cough46.741.244.4
Chest pain44.239.245.9
Angiomyolipoma38.176.5†43.0‡
Wheezing37.033.333.8
Abdominal bloating32.627.529.5
Abdominal pain20.031.4†18.4
Coughing chyle17.721.617.9
Breathlessness at rest17.419.614.5
Oedema arms or legs16.629.4†15.9
Fluid in chest/chylothorax15.917.711.1
Weight loss12.519.613.0
Respiratory failure2.55.92.9
History of pneumothorax63.1*64.7NA