Mean (SD) strength and bulk of respiratory and quadriceps muscles in the study population
| CF patients | Controls | Mean (95% CI)difference* | p value | |
|---|---|---|---|---|
| Pdi, trandiaphragmatic pressure elicited by twitch stimulation of the phrenic nerves; Mdi, diaphragm mass; LBM, lean body mass; Pga, change in gastric pressure elicited by abdominal stimulation; Tab, cumulative thickness of abdominal muscles; PT, peak torque of quadriceps muscle; quadCSA, cross sectional area of quadriceps muscle. *Mean difference between CF and control groups. | ||||
| Pdi (cm H2O) | 24.3 (4.5) | 27.0 (7.1) | −2.6 (−8.1 to 2.9) | NS |
| Mdi (g) | 183 (53) | 148 (46) | 35 (−10 to 79) | NS |
| Mdi/LBM (g/kg) | 4.22 (1.22) | 2.87 (0.49) | 1.34 (0.52 to 2.16) | 0.002 |
| Pga (cm H2O) | 91.1 (28.8) | 92.2 (27.5) | −1.13 (−26.7 to 24.4) | NS |
| Tab (mm) | 21.3 (4.7) | 26.5 (5.8) | −5.3 (−9.9 to −0.6) | 0.02 |
| Tab/LBM (mm/kg) | 0.49 (0.09) | 0.52 (0.06) | −0.04 (−0.1 to 0.03) | NS |
| PT (Nm) | 103.6 (33.4) | 154.4 (47.0) | −50.8 (−86.9 to −14.8) | 0.006 |
| quadCSA (cm2) | 48.5 (13.8) | 70.5 (15.7) | −22.0 (−35.1 to −9.0) | 0.001 |
| quadCSA/LBM (cm2/kg) | 1.10 (0.26) | 1.39 (0.10) | −0.29 (−0.46 to −0.12) | 0.001 |