Predictors of mortality: multivariate analysis
| Hazard ratio(adjusted) | 95% CI | p value | |
|---|---|---|---|
| BMI, body mass index; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; Pao2, Paco2, arterial oxygen and carbon dioxide tensions; Fio2, fractional inspired oxygen; LTOT, long term oxygen therapy. | |||
| Group A, no acute exacerbations of COPD; group B, 1–2 acute exacerbations of COPD (emergency visits or hospital admissions); group C, ⩾3 acute exacerbations of COPD. | |||
| Age (years) | 0.001 | ||
| <65 | Reference | – | |
| 65–74 | 1.92 | 0.64 to 5.25 | |
| ⩾75 | 5.28 | 1.75 to 15.93 | |
| Charlson index | 0.101 | ||
| 0 | Reference | – | |
| 1 | 1.17 | 0.59 to 2.29 | |
| ⩾2 | 2.23 | 1.06 to 4.69 | |
| BMI (kg/m2) | 0.96 | 0.89 to 1.03 | 0.245 |
| FEV1 (% predicted) | 0.97 | 0.96 to 1.03 | 0.810 |
| FVC (% predicted) | 0.97 | 0.97 to 1.02 | 0.695 |
| Pao2/Fio2 | 1.00 | 0.99 to 1.01 | 0.374 |
| Paco2 | 1.07 | 1.02 to 1.12 | 0.006 |
| LTOT | 1.95 | 0.93 to 4.12 | 0.078 |
| Exacerbation groups | 0.003 | ||
| Group A | Reference | – | |
| Group B | 2.00 | 1.01 to 3.98 | |
| Group C | 4.13 | 1.80 to 9.45 | |