Blood levels after therapeutic and subtherapeutic CPAP
| Change after therapeutic CPAP | p value | Change after subtherapeutic CPAP | p value | Between group difference | p value (between group changes)§ | |
|---|---|---|---|---|---|---|
| Values are mean (SD) with 95% confidence interval (CI). | ||||||
| *Laboratory reference range | ||||||
| †No laboratory reference range as new test | ||||||
| ¶Non-fasting levels. | ||||||
| §Significance of the difference between the change in the two treatment groups (unpaired t test). | ||||||
| Cholesterol (mmol/l)3.9–7.8* | −0.28 (0.88)(−0.45 to −0.11)n = 106 | 0.001 | −0.07 (0.68)(−0.06 to 0.21)n = 107 | 0.24 | 0.20(−0.12 to 0.41) | 0.06 |
| Triglyceride (mmol/l)0.55–1.9* (fasting) | −0.24 (0.26)¶(−0.28 to 0.76)n = 52 | 0.37 | −0.05 (1.4)¶(−0.45 to 0.36)n = 49 | 0.82 | 0.18(−0.50 to 0.86) | 0.60 |
| FXIIa (ng/ml)† | −0.08 (0.87)(−0.27 to 0.43)n = 26 | 0.65 | −0.14 (0.57)(−0.13 to 0.40)n = 20 | 0.30 | −0.13(−0.55 to 0.30) | 0.55 |
| FVIIa (mU/ml)† | 2.38 (25.1)(−12.5 to 7.8)n = 26 | 0.63 | −18.3 (26.7)(5.05 to 31.6)n = 18 | 0.01 | −20.7(−36.6 to −4.8) | 0.01 |
| s-Psel (ng/ml)† | −4.23 (42.5)(−0.83 to 16.7)n = 47 | 0.50 | −7.3 (35.6)(−3.3 to 17.9)n = 46 | 0.17 | 3.10(−13.1 to 19.3) | 0.71 |
| TAT (μg/l)† | 9.31 (43.5)(−26.9 to 8.24)n = 26 | 0.29 | 1.0 (42.9)(−21.1 to 19.0)n = 20 | 0.91 | −8.3(−34.2 to 17.7) | 0.52 |
| vWF Ag (IU/dl)50–200* | 2.1 (22.4)(−8.9 to 4.7)n = 44 | 0.54 | −1.8 (24.0)(−5.3 to 8.9)n = 46 | 0.62 | 3.87(−5.9 to 13.6) | 0.61 |
| Fibrinogen (g/l)1.5–4.0* | 0.05 (0.3)(−0.18 to 0.07)n = 26 | 0.37 | −0.03 (0.54)(−0.23 to 0.28)n = 20 | 0.84 | −0.08(−0.33 to 0.18) | 0.54 |
| FVII (IU/dl)50–200* | −5.3 (17.8)(−0.18 to 0.07)n = 26 | 0.14 | 0.7 (18.1)(−9.2 to 7.7)n = 20 | 0.86 | 6.0(−4.7 to 16.8) | 0.27 |
| FVIII (IU/dl)50–200* | −6.0 (19.5)(−1.9 to 13.9)n = 26 | 0.13 | 0.7 (19.4)(−9.8 to 8.4)n = 20 | 0.87 | 6.7(−5.0 to 18.3) | 0.26 |
| FXII (IU/dl)50–200* | −4.1 (16.6)(−2.6 to 10.8)n = 26 | 0.22 | 8.5 (15.7)(−15.8 to −1.1)n = 20 | 0.03 | 12.5(2.8 to 22.2) | 0.01 |
| Homocysteine (μmol/l)5–15* | −0.64 (4.8)(−2.0 to 0.70)n = 52 | 0.34 | 0.26 (3.4)(−1.23 to 0.72)n = 49 | 0.60 | 0.18(−1.51 to 1.87) | 0.83 |