Sleep apnoea severity, sleep quality, nasal airflow resistance, and diary record details during treatment with fluticasone and placebo
| Variable | Total population (n = 23) | Apnoeic snorers (group A) (n = 13) | Non-apnoeic snorers (group S) (n = 10) | |||
|---|---|---|---|---|---|---|
| F | P | F | P | F | P | |
| Data are shown as median (quartile range). | ||||||
| AHI = apnoea/hypopnoea index; NAR = nasal airway resistance; TST = total sleep time; TOT = total sleep period time; REM = rapid eye movement sleep; Sao2 = percentage arterial oxygen saturation; F = fluticasone; P = placebo. | ||||||
| *p<0.05; **p<0.01. | ||||||
| AHI | 11.9 (22.6)* | 20 (26.3) | 23.3 (21.3)* | 30.3 (31.9) | 2.7 (2.15) | 5.0 (6.3) |
| NAR | 2.74 (1.21)** | 3.27 (1.38) | 2.88 (1.49)** | 3.17 (1.6) | 2.71 (0.76) | 3.47 (1.19) |
| TST | 394 (47.5) | 382 (37) | 389.5 (53.8) | 380.5 (30.8) | 397.5 (46.3) | 391.8 (59.5) |
| TST/TOT (%) | 93.6 (8.3) | 92.1 (7.4) | 91.7 (10.2) | 91.7 (6.1) | 95.3 (8.5)* | 93.5 (12.7) |
| Stage 1 (%) | 9.4 (10.1) | 10.0 (10.1) | 12.1 (9.8) | 11.7 (4.4) | 8.3 (5.5) | 7.9 (2.4) |
| Stage 2 (%) | 53.7 (18.9)* | 63.5 (19.8) | 59.8 (15.8) | 67.3 (14.7) | 47.4 (10.5) | 58.1 (21.5) |
| Stage 3 (%) | 9.0 (8.6) | 6.4 (8.7) | 7.4 (11.0) | 5.1(8.7) | 9.8 (8.0) | 8.4 (4.8) |
| Stage 4 (%) | 7.8 (17.3) | 4.6 (10.6) | 0 (5.9) | (5.5) 12.2 | 2.0 (16.8) | 5.6 (13.3) |
| Stage REM (%) | 13.4 (10.4) | 12.5 (5.3) | 10.9 (8.0) | 10.5 (4.2) | 17.1 (11.2) | 14.8 (5.7) |
| Mean Sao2 | 94.6 (2.37) | 94.6 (2.73) | 94.4 (2.0) | 94.3 (2.41) | 95.9 (2.5) | 95.3 (3.1) |
| Minimum Sao2 | 82 (10) | 83 (14) | 78 (11.5) | 78 (14) | 85.5 (6.5) | 86 (15.5) |
| Subjective nasal congestion | 2.2 (0.8)* | 2.3 (0.6) | 2.4 (1.0) | 2.6 (0.9) | 2.0 (1.1)** | 2.3 (0.3) |
| Daytime alertness | 2.2 (0.7)* | 2.3 (0.9) | 2.1 (0.7) | 2.2 (0.7) | 2.3 (1.1)* | 2.5 (0.5) |
| Subjective sleep quality | 1.8 (1.0) | 2.0 (0.9) | 1.7 (1.0) | 1.8 (1.1) | 1.9 (1.1) | 2.2 (1.1) |
| Partner-reported snoring | 2.9 (1.4) | 2.9 (1.5) | 3.3 (1.4) | 3.3 (1.8) | 2.5 (0.9) | 2.7 (0.6) |