Table 4

 Ventilatory pattern and metabolic data in resting conditions and at end of exercise after placebo and after bronchodilator (BD) treatment with salbutamol in improvers and non-improvers

ImproversNon-improvers
PlaceboBDPlaceboBD
Values are expressed as mean (SE).
**p<0.01 (BD v placebo).
†p<0.05 (improvers v non-improvers).
At rest
    V˙e (l/min)15.6 (0.8)16.4 (1.9)17.7 (1.1)16.6 (2.2)
    V˙o2 (l/min)0.39 (0.08)0.35 (0.02)0.35 (0.03)0.29 (0.02)
    V˙co2 (l/min)0.28 (0.02)0.30 (0.02)0.30 (0.04)0.25 (0.03)
    RER0.84 (0.02)0.86 (0.03)0.84 (0.05)0.85 (0.06)
    HR (beats/min)95.3 (4.1)87.0 (2.0)82.6 (6.1)92.3 (3.9)
    V˙o2/HR (ml/beat)3.5 (0.3)4.1 (0.2)4.0 (0.4)3.2 (0.3)†
    Breathlessness0.9 (0.4)1.2 (0.4)0.5 (0.2)0.8 (0.3)
    Leg effort0.9 (0.3)0.8 (0.3)0.4 (0.2)0.9 (0.5)
At end of exercise
    V˙e (l/min)47.3 (2.9)43.8 (3.7)36.3 (3.4)†37.1 (3.1)
    V˙o2 (l/min)0.94 (0.06)0.99 (0.07)0.92 (0.08)0.86 (0.06)
    V˙co2 (l/min)0.90 (0.07)0.96 (0.08)0.82 (0.06)0.82 (0.06)
    RER0.95 (0.03)0.97 (0.04)0.90 (0.03)0.95 (0.01)
    HR (beats/min)114.1 (6.2)117.0 (6.3)105.4 (3.2)115.0 (3.3)
    V˙o2/HR (ml/beat)8.4 (0.5)8.7 (0.9)9.4 (0.8)7.6 (0.8)**
    Breathlessness6.4 (0.5)7.0 (0.6)4.0 (0.6)†4.8 (0.7)†
    Leg effort6.0 (0.7)6.5 (0.9)4.0 (0.6)5.0 (0.5)