Table 3

Baseline characteristics of patients who completed follow up according to the number of COPD exacerbations

Patients with infrequent exacerbations* (n = 178)Patients with frequent exacerbations† (n = 158)p value
Values are mean (SD) unless otherwise specified.
BMI = body mass index; COPD = chronic obstructive pulmonary disease; FVC = forced vital capacity; FEV1 = forced expiratory volume in 1 second; SGRQ = St George’s Respiratory Questionnaire; PCS = physical summary; MCS = mental summary.
*<3 in 2 years.
†⩾3 in 2 years.
Baseline characteristics
Sex (no (%) male)174 (97.8%)154 (97.5%)0.864
Age (years)66.5 (7.9)65.6 (8.5)0.304
BMI (kg/m2)27.8 (3.9)27 (4.1)0.076
Years of evolution of COPD12.2 (9)13.9 (8.4)0.079
Severity of COPD, n (%)
    II (FEV1 35%–49%)90 (50.6%)57 (36.1%)0.008
    III (FEV1 <35%)88 (49.4%)101 (63.9%)
Pack years53.1 (31.3)57.1 (29.1)0.222
Coexisting chronic conditions, n (%)
    055 (30.9%)47 (29.7%)0.396
    161 (34.3%)43 (27.2%)
    229 (16.3%)34 (21.5%)
    3 or more33 (18.5%)34 (21.5%)
Hospital admission
    No141 (79.2%)92 (58.2%)<0.001
    Yes37 (20.8%)66 (41.8%)
Spirometric values
    FVC, ml2254.2 (675.7)2186.8 (597.8)0.336
    FVC, %54.5 (13.9)52.6 (12.8)0.184
    FEV1, ml1047.9 (298)981.6 (271.6)0.034
    %FEV1 over predicted34.2 (8.0)31.8 (8.0)0.006
    FEV1/FVC, %65.4 (13.8)62.9 (13.8)0.095
Quality of life scores
    SGRQ Symptoms44.8 (20.1)52.2 (19.6)0.001
    SGRQ Activity59.2 (22)66.8 (18.9)0.001
    SGRQ Impacts35.5 (18.3)42.4 (16.5)<0.001
    SGRQ Total44.2 (17.9)51.4 (15.6)<0.001
    PCS1239.5 (9.7)36.7 (8.3)0.006
    MCS1250.5 (12.2)48.6 (12.7)0.168
Quality of life scores at the end of follow up
    SGRQ Symptoms34.04 (18.64)46.63 (18.91)<0.001
    SGRQ Activity59.94 (19.98)67.95 (18.57)<0.001
    SGRQ Impacts29.90 (18.35)38.25 (18.40)<0.001
    SGRQ Total39.16 (16.81)48.45 (16.09)<0.001
    PCS1240.32 (9.26)36.73 (9.12)0.001
    MCS1251.06 (12.11)50.16 (11.83)0.502