Table 2

Genotype and allele frequencies for interferon-γ receptor 1 (IFNGR1) gene polymorphisms

PolymorphismGenotype frequencies, n (%)*Allele frequenciesOdds ratio (95% CI)†p value‡
*Total number genotyped  =  297 cases and 285 controls: discrepancies in numbers arise from genotyping failures.
†Odds ratio (OR) and p values shown are for Fisher’s exact test comparison of 2 × 2 tables for allele frequencies between cases and controls.
‡No multiple testing correction was applied.
−611AAAGGGA/G
    Cases273 (93.2)19 (6.4)1 (0.4)0.96/0.041.19 (0.66 to 2.17)0.34
    Controls260 (91.9)22 (7.7)1 (0.4)0.96/0.040.84 (0.46 to 1.53)
−470TT/TTTT/−−/−TT/−
    Cases234 (79.6)53 (18.0)7 (2.4)0.89/0.110.83 (0.57 to 1.22)0.20
    Controls232 (81.7)49 (17.3)3 (1)0.90/0.101.20 (0.82 to 1.75)
−270TTTCCCT/C
    Cases244 (95.7)10 (3.9)1 (0.4)0.98/0.020.91 (0.39 to 2.13)0.50
    Controls225 (96.5)6 (2.6)2 (0.9)0.98/0.021.10 (0.47 to 2.57)
−56TTTCCCT/C
    Cases62 (27.9)108 (48.7)52 (23.4)0.52/0.481.01 (0.78 to 1.30)0.50
    Controls73 (27.5)130 (49.1)62 (23.4)0.52/0.480.99 (0.77 to 1.28)
+95TTTCCCT/C
    Cases74 (27.4)131 (48.5)65 (24.1)0.52/0.480.98 (0.77 to 1.25)0.49
    Controls73 (27.5)130 (49.1)62 (23.4)0.52/0.481.02 (0.80 to 1.29)
E7+189TTTGGGT/G
    Cases255 (95.1)13 (4.9)0 (0)0.97/0.031.41 (0.68 to 2.91)0.23
    Controls249 (93.6)16 (6.0)1 (0.4)0.97/0.030.71 (0.34 to 1.46)