Baseline | Epoprostenol | ||
---|---|---|---|
6 months* | 17 months† | ||
*Epoprostenol dose 24 ng/kg/min. | |||
†Epoprostenol dose 26 ng/kg/min. | |||
‡Thrombosis of the anterior leaflet of the St Jude valve led to mild increases in pulmonary artery occlusion pressure at 6 months and 17 months after epoprostenol was started. | |||
Mean systemic arterial pressure (mm Hg) | 83 | 83 | 90 |
Mean right atrial pressure (mm Hg) | 12 | 16 | 16 |
Mean pulmonary artery pressure (mm Hg) | 65 | 55 | 57 |
Cardiac output (l/min) | 2.2 | 2.9 | 3.2 |
Pulmonary artery occlusion pressure (mm Hg) | 12 | 16‡ | 18‡ |
Left ventricular end diastolic pressure (mm Hg) | 12 | 7 | – |
Pulmonary vascular resistance (dyne.s/cm5) | 1560 | 1072 | 999 |