Odds ratios, coefficients and 95% confidence intervals from cross sectional time series analyses of asthma, wheeze, asthma treatment, time off school/work due to asthma, bronchial responsiveness, atopy, FEV1/FVC ratio, and log serum IgE on childhood socioeconomic status (SES; 1 = professional, 6 = manual labourer)
| Adjusted for sex only | Fully adjusted | |||||
|---|---|---|---|---|---|---|
| n | OR | 95% CI | n | OR | 95% CI | |
| Current asthma | 6104 | 1.07 | 0.94 to 1.21 | 4939 | 1.07 | 0.92 to 1.25 |
| Wheeze | 6096 | 1.04 | 0.96 to 1.13 | 4937 | 1.05 | 0.96 to 1.16 |
| Asthma treatment | 6099 | 1.05 | 0.92 to 1.19 | 4936 | 1.05 | 0.90 to 1.22 |
| Time off school/work | 5278 | 1.08 | 0.93 to 1.26 | 4220 | 1.11 | 0.94 to 1.30 |
| Bronchial response* | 5656 | 1.07 | 0.94 to 1.21 | 4632 | 1.03 | 0.88 to 1.20 |
| Atopy | 1593 | 0.90** | 0.80 to 1.00 | 1299 | 0.89 | 0.78 to 1.02 |
| n | Coefficient | 95% CI | n | Coefficient | 95% CI | |
|---|---|---|---|---|---|---|
| n = number of observations in each analysis (several observations made for each subject at different ages); OR = odds ratio (change in odds of the outcome for each point change in the SES scale); coefficient = change in prevalence of outcome for each point change in the SES scale; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity. | ||||||
| *Bronchial responsiveness means a response to methacholine or salbutamol as defined in the text. Fully adjusted figures are adjusted for sex, breast feeding, parental asthma, parental smoking, birth order, and smoking during pregnancy. | ||||||
| **p<0.05. | ||||||
| FEV1/FVC ratio | 5860 | −0.13 | −0.46 to 0.20 | 4792 | −0.03 | −0.42 to 0.37 |
| Log IgE | 1350 | 0.03 | −0.06 to 0.12 | 1095 | 0.01 | −0.10 to 0.11 |