Multivariable associations of birth weight with FVC
Difference (95% confidence interval) in FVC (l) | ||||
---|---|---|---|---|
Model 1* | Model 2† | Model 3‡ | Model 4§ | |
FVC, forced vital capacity. | ||||
*Model 1: adjusted for age and examining nurse. | ||||
†Model 2: adjusted for age, examining nurse and height squared. | ||||
‡Model 3: adjusted for age, examining nurse, height squared, father’s occupational social class, whether childhood house had a bathroom, whether childhood house had hot water, family access to a car in childhood, whether the participant shared a bedroom as a child, age at leaving full time education, adult occupational social class, adult car access, adult home ownership, pension arrangements. | ||||
§Model 4: adjusted for all factors in model 3 and adult smoking. | ||||
Lowest quarter birth weight,range 739–2826 g (N = 746) | Reference | Reference | Reference | Reference |
2nd quarter birth weight,range 2827–3352 g (N = 476) | 0.15 (0.04 to 0.26) | 0.07 (−0.04 to 0.17) | 0.04 (−0.06 to 0.15) | 0.04 (−0.06 to 0.14) |
3rd quarter birth weight, range 3353–3735 g (N = 774) | 0.18 (0.09 to 0.27) | 0.06 (−0.03 to 0.17) | 0.06 (−0.03 to 0.15) | 0.06 (−0.03 to 0.15) |
Highest quarter birth weight,range 3736–5909 g (N = 435) | 0.19 (0.08 to 0.30) | 0.02 (−0.08 to 0.13) | 0.01 (−0.09 to 0.12) | 0.02 (−0.09 to 0.12) |
Per 1 kg birth weight | 0.10 (0.05 to 0.15) | 0.02 (−0.03 to 0.07) | 0.02 (−0.03 to 0.07) | 0.02 (−0.02 to 0.07) |
p linear trend | <0.001 | 0.42 | 0.41 | 0.31 |
p non-linear association | 0.24 | 0.19 | 0.35 | 0.34 |
Per 1 kg excluding those in lowest birth weight quarter | 0.02 (−0.07 to 0.11) | −0.04 (−0.13 to 0.05) | −0.02 (−0.11 to 0.07) | −0.01 (−0.10 to 0.08) |