Relationship between expected and diagnosed cases of AAT deficiency (Pi ZZ + Pi SZ) in selected countries
| Country | AAT deficiency expected | AAT deficiency diagnosed |
|---|---|---|
| Expected cases are based on de Serres13 and Martin et al26; diagnosed cases are from Alpha One International Registry (AIR) central database (updated April 2003, courtesy of Claes-Göran Löfdahl, Eeva Piitulainen, Ragnar Alm). Individuals with AAT deficiency in the AIR database were recruited since 1999 in a prospective fashion. | ||
| Canada | 42372 | 144 |
| Italy | 46068 | 100 |
| The Netherlands | 9790 | 136 |
| New Zealand/Australia | 33707 | 93 |
| Spain | 86899 | 90 |
| Sweden | 6717 | 181 |
| UK | 79456 | 324 |
| Total | 305009 | 1068 |