Table 1

 Characteristics of ibuprofen study subjects (n = 14)*

FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity.
*Data refer to patients who completed the study and are expressed as mean (SE).
†All the patients had a smoking history of more than 10 pack years.
‡Atopy was an exclusion criterion. Absence of atopy was confirmed by skin prick testing.
Six of the 14 patients were treated with inhaled corticosteroids: beclomethasone dipropionate (dose range 0.2–1 mg/day), budesonide (dose range 0.4–0.8 mg/day).
Age (years)63 (3)
F/M6/8
SmokingEx-smokers
Pack years†>10
FEV1 (l)0.96 (0.11)
FVC (l)2.06 (0.14)
FEV1 (% pred)38.2 (3.8)
FVC (% pred)65.9 (3.8)
FEV1/FVC (%)45.8 (2.8)
Change in FEV1 post-bronchodilator (% pred)2.3 (1.1)
Atopy‡No
Treatment
    β2 agonists4
    Anticholinergics6