Characteristics of ibuprofen study subjects (n = 14)*
| FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity. | |
| *Data refer to patients who completed the study and are expressed as mean (SE). | |
| †All the patients had a smoking history of more than 10 pack years. | |
| ‡Atopy was an exclusion criterion. Absence of atopy was confirmed by skin prick testing. | |
| Six of the 14 patients were treated with inhaled corticosteroids: beclomethasone dipropionate (dose range 0.2–1 mg/day), budesonide (dose range 0.4–0.8 mg/day). | |
| Age (years) | 63 (3) |
| F/M | 6/8 |
| Smoking | Ex-smokers |
| Pack years† | >10 |
| FEV1 (l) | 0.96 (0.11) |
| FVC (l) | 2.06 (0.14) |
| FEV1 (% pred) | 38.2 (3.8) |
| FVC (% pred) | 65.9 (3.8) |
| FEV1/FVC (%) | 45.8 (2.8) |
| Change in FEV1 post-bronchodilator (% pred) | 2.3 (1.1) |
| Atopy‡ | No |
| Treatment | |
| β2 agonists | 4 |
| Anticholinergics | 6 |