Most parsimonious multivariate models for two measures of bone mineral density (lumbar spine and principal component) in children/adolescents and adults with CF
| Overall | Variable* | Parameter estimates | (95% CI) | ||
|---|---|---|---|---|---|
| N | r2 | ||||
| BMI = body mass index; FEV1 = forced expiratory volume in 1 second. | |||||
| *After adjusting for age and sex. | |||||
| †Defined as 5–18 years for females and 5–20 years for males. | |||||
| ‡Defined as >18 years for females and >20 years for males. | |||||
| Children/adolescents† | |||||
| Lumbar spine | 85 | 0.78 | Body cell mass | 0.02 | (0.01 to 0.02) |
| No of days in hospital | −0.002 | (−0.004 to −0.001) | |||
| BMI | 0.01 | (0.00 to 0.02) | |||
| No of hospital admissions | 0.02 | (0.00 to 0.04) | |||
| Principal component | 74 | 0.85 | BMI | 0.13 | (0.05 to 0.21) |
| Body cell mass | 0.15 | (0.08 to 0.22) | |||
| FEV1 | 0.01 | (0.00 to 0.02) | |||
| Adults‡ | |||||
| Lumbar spine | 32 | 0.28 | Activity questionnaire score | 0.09 | (0.03 to 0.14) |
| Principal component | 32 | 0.62 | Body cell mass | 0.14 | (0.06 to 0.22) |
| No of days in hospital | 0.01 | (0.00 to 0.02) | |||