Table 3

 Factors associated with paradoxical reaction (PR) in patients starting HAART after commencing antituberculous treatment

No (%) with PRp value*
*Fisher’s exact test.
CD4 count at starting HAART
    >50 cells/mm34/17 (24%)0.7
    <50 cells/mm34/11 (36%)
Viral load at starting HAART
    <5.5 log copies/ml3/14 (21%)0.7
    >5.5 log copies/ml5/14 (36%)
Disseminated TB
    No2/15 (13%)0.09
    Yes6/13 (46%)
CD4 cell response to HAART
    >100 cells/mm3 increase6/18 (33%)0.7
    <100 cells/mm3 increase2/10 (20%)
Viral load (VL) response to HAART
    Achieved VL <400 copies/ml8/24 (33%)0.3
    Did not achieve VL <400 copies/ml0/4 (0%)
Ethnicity
    Black African5/16 (31%)1.0
    Other3/12 (25%)
Time from TB treatment to HAART
    <6 weeks7/13 (54%)0.03
    6 weeks–6 months1/11 (9%)
    >6 months0/4 (0%)