Comparison of frequency, manifestations, and treatment of paradoxical reactions (PR) between HIV+TB+ and HIV−TB+ patients
| HIV+ve(n = 50) | HIV−ve(n = 50) | |
|---|---|---|
| PR | 14 (28%) | 5 (10%) |
| Disseminated TB and PR | 9 (65%) | 4 (80%) |
| Median (range) time from starting TB medication to onset of PR (days) | 33 (3–173) | 87 (23–157) |
| Median (range) time from starting HAART to onset of PR (days) | 11 (8–18) | NA |
| PR treated with corticosteroids | 8 | 1 |
| Manifestations of PR | ||
| Fever | 4 | 2 |
| Ascites | 1 | 0 |
| Lymph nodes | 7 | 2 |
| CNS | 2 | 0 |
| Respiratory | 2 | 0 |
| Pleural effusion | 1 | 1 |
| Ocular | 0 | 1 |
| Joint swelling | 0 | 1 |
| >1 manifestation of PR | 4 | 2 |