Analysis of factors affecting mortality using the univariate Cox proportional hazards model
| Hazards ratio (95% CI) | p value | |
|---|---|---|
| INR=international normalised ratio; aPTT=thromboplastin time. | ||
| *p<0.05. | ||
| †Reference group is patients having no comorbidity. | ||
| ‡Per unit increase of the variable. | ||
| Sex (male) | 1.6 (0.6 to 4.0) | 0.320 |
| Age (>60 years) | 6.8 (2.5 to 18.4) | <0.001* |
| Presence of comorbidity | 9.0 (3.2 to 25.3) | <0.001* |
| Diabetes mellitus (DM) | 4.7 (1.5 to 14.3) | 0.008* |
| Cardiac disease | 9.2 (3.5 to 23.9) | <0.001* |
| Presence of DM and/or cardiac disease† | 12.5 (4.1 to 37.7) | <0.001* |
| Presence of other comorbidities† | 5.6 (1.5 to 20.8) | 0.010* |
| Multilobar radiological abnormality | 2.0 (0.8 to 5.0) | 0.167 |
| Temperature (°C)‡ | 1.4 (0.7 to 3.0) | 0.335 |
| Oxygen saturation (%)‡ | 0.9 (0.8 to 1.1) | 0.399 |
| Total white cell count (109/l)‡ | 1.1 (1.0 to 1.2) | 0.153 |
| Neutrophil (109/l)‡ | 1.1 (1.0 to 1.2) | 0.073 |
| Lymphocyte (109/l) | 2.3 (0.6 to 8.0) | 0.205 |
| Platelet count (109/l)‡ | 1.0 (1.0 to 1.0) | 0.823 |
| Serum sodium (mmol/l)‡ | 1.0 (0.9 to 1.2) | 0.857 |
| Serum urea (mmol/l)‡ | 1.2 (1.0 to 1.4) | 0.017* |
| Alanine aminotransferase (IU/l)‡ | 1.0 (1.0 to 1.0) | 0.097 |
| Prolonged INR (>1.2 seconds) | 3.1 (0.7 to 13.4) | 0.135 |
| Prolonged aPTT (>42 seconds) | 3.3 (1.2 to 8.9) | 0.018* |
| High creatine kinase (>330 IU/l) | 2.3 (0.9 to 6.1) | 0.100 |
| High lactate dehydrogenase (>450 IU/l) | 4.8 (1.4 to 16.6) | 0.014* |