Spearman rank correlations (and p values) between plasma fatty acids and markers of asthma severity (see text)
| Type of fatty acid | No of attacks in previous 3 months (n = 175) | Bronchial reactivity logDRS (n = 1013) |
|---|---|---|
| logDRS = log dose-response slope. | ||
| n-6 series polyunsaturated | ||
| 18:2 LA | 0.153 (p = 0.043) | 0.055 |
| 18:3 GLA | −0.013 | 0.006 |
| 20:2 | −0.044 | 0.099 (p = 0.002) |
| 20:3 DHGLA | 0.03 | 0.097 (p = 0.002) |
| 20:4 AA | −0.032 | −0.034 |
| 22:4 | −0.044 | 0.042 |
| 22:5 | 0.031 | 0.085 (p = 0.007) |
| n-3 series polyunsaturated | ||
| 18:3 LNA | −0.106 | 0.033 |
| 20:5 EPA | −0.129 | −0.053 |
| 22:5 DPA | −0.076 | −0.035 |
| 22:6 DHA | −0.098 | −0.07 (p = 0.026) |
| Total | ||
| n-6 | 0.143 | 0.069 (p = 0.029) |
| n-3 | −0.155 (p = 0.04) | −0.074 (p = 0.019) |
| n-6:n-3 | 0.178 (p = 0.019) | 0.081 (p = 0.01) |
| Polyunsaturated | 0.058 | −0.047 |
| Saturated | 0.007 | −0.043 |
| Trans | 0.065 | 0.023 |
| Monounsaturated | −0.079 | 0.045 |