Unadjusted odds ratios (95% CI) for associations between plasma fatty acids (per 1% increase) and asthma and/or atopy
Type of fatty acid | Current asthma (n = 950) | Asthma (n = 1009) | Doctor diagnosed asthma (n = 1007) | Atopy (n = 1009) |
---|---|---|---|---|
n-6 series polyunsaturated | ||||
18:2 LA | 1.009 (0.95 to 1.07) | 0.96 (0.92 to 1.01) | 1.001 (0.95 to 1.05) | 1.0 (0.96 to 1.04) |
18:3 GLA | 2.14 (0.12 to 37.1) | 0.50 (0.05 to 5.51) | 1.45 (0.14 to 14.8) | 17.8 (2.00 to 158) |
20:2 | 3.98 (0.50 to 31.9) | 6.85 (1.21 to 38.9) | 11.6 (2.14 to 63.3) | 0.26 (0.06 to 1.26) |
20:3 DHGLA | 1.44 (1.19 to 1.74) | 1.38 (1.17 to 1.62) | 1.26 (1.08 to 1.48) | 1.06 (0.92 to 1.22) |
20:4 AA | 0.996 (0.91 to 1.09) | 1.07 (0.99 to 1.15) | 0.95 (0.89 to 1.03) | 1.00 (0.94 to 1.07) |
22:4 | 1.82 (0.50 to 6.64) | 2.09 (0.66 to 6.61) | 1.16 (0.36 to 3.68) | 1.21 (0.48 to 3.07) |
22:5 | 3.02 (1.02 to 8.96) | 4.31 (1.71 to 10.9) | 2.63 (1.05 to 6.58) | 0.997 (0.41 to 2.42) |
n-3 series polyunsaturated | ||||
18:3 LNA | 1.004 (0.12 to 8.12) | 0.16 (0.03 to 1.01) | 1.24 (0.23 to 7.00) | 0.77 (0.17 to 3.54) |
20:5 EPA | 0.93 (0.66 to 1.30) | 0.96 (0.73 to 1.26) | 0.88 (0.67 to 1.15) | 1.001 (0.79 to 1.27) |
22:5 DPA | 1.26 (0.83 to 1.89) | 1.48 (1.05 to 2.08) | 0.90 (0.63 to 1.27) | 1.36 (0.99 to 1.88) |
22:6 DHA | 0.95 (0.86 to 1.06) | 1.04 (0.95 to 1.13) | 0.97 (0.89 to 1.06) | 0.94 (0.87 to 1.01) |
Total | ||||
n-6 | 1.07 (0.99 to 1.14) | 1.04 (0.98 to 1.10) | 1.10 (0.95 to 1.07) | 1.01 (0.96 to 1.05) |
n-3 | 0.97 (0.90 to 1.06) | 1.03 (0.96 to 1.10) | 0.97 (0.91 to 1.04) | 0.97 (0.92 to 1.03) |
n-6:n-3 | 1.07 (0.95 to 1.19) | 0.995 (0.90 to 1.09) | 1.07 (0.98 to 1.18) | 1.05 (0.97 to 1.15) |
Polyunsaturated | 1.002 (0.95 to 1.05) | 1.02 (0.98 to 1.07) | 0.98 (0.95 to 1.03) | 0.99 (0.95 to 1.03) |
Saturated | 0.96 (0.90 to 1.03) | 0.92 (0.88 to 0.97) | 0.98 (0.93 to 1.03) | 1.004 (0.96 to 1.06) |
Trans | 0.91 (0.42 to 1.95) | 0.81 (0.43 to 1.51) | 1.24 (0.68 to 2.27) | 1.23 (0.71 to 2.14) |
Monounsaturated | 1.02 (0.92 to 1.15) | 1.10 (1.005 to 1.21) | 1.10 (1.002 to 1.20) | 1.04 (0.96 to 1.12) |