Associations between C-reactive protein (CRP) and demographic, cardiovascular, biological, and respiratory factors
| CRP | p value | ||
|---|---|---|---|
| Lower tertiles (n = 173) | High tertile (n = 86) | ||
| Tertiles are sex dependent (tertile limits in men: <0.7 mg/l, 1.3 mg/l, 1.4–12.5 mg/l; in women: <0.4 mg/l, 1.2 mg/l, 1.3–11.7 mg/l). | |||
| BMI, body mass index; HDL, high density level; LDL, low density level; BHR, bronchial hyperresponsiveness; CRP, C-reactive protein; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity. | |||
| *Values are mean (SD). | |||
| †Both parents of white ethnic origin. | |||
| ‡On 171 subjects. | |||
| ¶Adjusted for age, sex, height, and smoking status. | |||
| Age (years)* | 44.4 (7.6) | 45.4 (6.8) | 0.30 |
| Men (%) | 54.9 | 54.7 | 1.00 |
| BMI (kg/m2)* | 22.9 (3.0) | 25.8 (3.9) | <0.001 |
| Age at leaving education (years)* | 21.5 (3.4) | 21.0 (4.0) | 0.30 |
| White ethnic origin† (%) | 95.3‡ | 94.2 | 0.70 |
| Systolic blood pressure (mm Hg)* | 118.9 (16.5) | 121.5 (15.9) | 0.20 |
| Diastolic blood pressure (mm Hg)* | 77.0 (10.3) | 78.5 (10.5) | 0.30 |
| Hypertension (%) | 12.7 | 25.6 | 0.009 |
| Total cholesterol (mg/dl)* | 249.6 (97.6) | 262.4 (114.9) | 0.40 |
| HDL cholesterol (mg/dl)* | 75.3 (2.6) | 71.5 (3.7) | 0.40 |
| LDL cholesterol (mg/dl)* | 147.0 (62.9) | 155.4 (76.6) | 0.40 |
| Hypercholesterolemia (%) | 21.4 | 27.9 | 0.20 |
| Smoking status | |||
| Never smokers (%) | 43.9 | 38.4 | 0.10 |
| Ex-smokers (%) | 29.5 | 22.1 | |
| Current smokers (%) | 26.6 | 39.5 | |
| Chronic bronchitis (%) | 4.1 | 7.0 | 0.30 |
| Asthma (%) | 11.0 | 14.0 | 0.50 |
| Adjusted¶ FEV1 (l/s)* | 3.50 (0.44) | 3.29 (0.44) | <0.001 |
| FEV1 (% pred)* | 107.60 (13.56) | 101.14 (13.39) | <0.001 |
| Adjusted¶ FVC (l/s)* | 4.16 (0.55) | 3.97 (0.55) | 0.01 |
| FEV1 % FVC* | 84.31 (6.02) | 83.29 (7.20) | 0.20 |
| BHR (%) | 24.86 | 41.86 | 0.005 |