Healthy elderly (n=18) | COPD patients (n=22) | p value | |
---|---|---|---|
Data expressed as mean (SD). | |||
FEV1=forced expiratory volume in 1 second; VC=vital capacity; TLC=total lung capacity; RV=residual volume; Tlco=carbon monoxide transfer factor; Pao2, Paco2=arterial oxygen and carbon dioxide tensions. | |||
Age (years) | 74.6 (6.3) | 68.6 (8.9) | 0.02 |
Height (m) | 1.66 (0.13) | 1.67 (0.10) | 0.91 |
Weight (kg) | 72.7 (13.3) | 72.8 (20.4) | 0.99 |
BMI (kg/m2) | 26.2 (3.8) | 26.2 (6.3) | 0.98 |
Fat free mass (kg) | 44.9 (9.0) | 47.7 (10.4) | 0.44 |
FEV1 (litres) | 2.6 (0.4) | 0.9 (0.3) | <0.0001 |
FEV1 (% pred) | 101 (8) | 38 (13) | <0.0001 |
FEV1/VC (%) | 75.6 | 37.6 | <0.0001 |
TLC (% pred) | – | 116.9 (18.0) | – |
RV (% pred) | – | 186.3 (48) | – |
Tlco (% pred) | – | 43.0 (15.5) | – |
Pao2 (kPa) | 10.2 (1.0) | 8.8 (1.4) | 0.08 |
Paco2 (kPa) | 5.5 (0.3) | 5.4 (0.9) | 0.81 |