Characteristics of smokers and confirmed ex-smokers who received prednisolone
| Ex-smokers (n=278) | Smokers (n=246) | p value | |
|---|---|---|---|
| Values are mean (SD) unless otherwise indicated. | |||
| FEV1=forced expiratory volume in 1 second; FVC=forced vital capacity. | |||
| Male (%) | 81.7 | 73.2 | 0.02 |
| Atopic (%) | 31.0 | 24.0 | 0.09 |
| Age | 65.8 (6.2) | 61.9 (7.2) | <0.001 |
| FEV1 pre-bronchodilator (l) | 1.18 (0.44) | 1.27 (0.46) | 0.030 |
| FEV1 pre-bronchodilator (% predicted) | 41.7 (14.9) | 44.7 (13.8) | 0.019 |
| FEV1 post-bronchodilator (l) | 1.36 (0.46) | 1.45 (0.49) | 0.042 |
| FEV1 post-bronchodilator (% predicted) | 48.0 (15.0) | 50.8 (14.1) | 0.025 |
| ΔFEV1 post-bronchodilator | 180 (125) | 178 (131) | 0.897 |
| FVC pre-bronchodilator (l) | 2.93 (0.69) | 2.98 (0.82) | 0.428 |
| FVC pre-bronchodilator (% predicted) | 80.8 (17.8) | 83.1 (16.9) | 0.138 |
| FVC post-bronchodilator (l) | 3.31 (0.69) | 3.34 (0.86) | 0.637 |
| FVC post-bronchodilator (% predicted) | 91.1 (16.4) | 92.9 (16.2) | 0.205 |
| Change in FEV1 (ml) following prednisolone (mean (SE) from multivariate model) | 74 (12) | 35 (11) | <0.01 |