Time course and outcome in empirical treatment failure
| Variable | Failure | No failure | p value | RR (95% CI) |
|---|---|---|---|---|
| Mean (SD) clinical stability (days) | 11.1 (8.6) | 4.1 (3.5) | 0.001 | |
| Complications (%) | 69.6 | 23.6 | 0.001 | 7.4 (5.5 to 9.9) |
| Renal insufficiency (%) | 21.5 | 6.7 | 0.001 | 3.8 (2.6 to 5.5) |
| Cardiac insufficiency (%) | 18.2 | 7. | 0.001 | 2.9 (1.9 to 4.3) |
| Liver disease (%) | 4.2 | 1.1 | 0.001 | 3.9 (1.8 to 8.8) |
| Shock (%) | 15.8 | 1.7 | 0.001 | 11 (6.9 to 17.8) |
| Respiratory insufficiency (%) | 45.8 | 10.5 | 0.001 | 7.2 (5.3 to 9.7) |
| ICU admission (%) | 26.2 | 3.9 | 0.001 | 8.6 (6 to 12.5) |
| Mean (SD) length of stay (days) | 18.5 (13.9) | 9.4 (5.7) | <0.001 | |
| Death (%) | 25.2 | 2.01 | 0.001 | 16 (11 to 24.6) |