Table 4

Parameters of lung function before and after inhalation therapy

Oxygen alone (n=17)Oxygen + NO (n=15)
Baseline3 monthsBaseline3 monthsp value
Values are mean (SD).
FEV1=forced expiratory vlume in 1 second; FEV1%FVC=forced expiratory volume in 1 second as a percentage of forced expiratory vital capacity; TLC=total lung capacity; RV=residual volume; RV%TLC=residual volume as a percentage of total lung capacity; Pao2=arterial oxygen tension; Paco2=arterial carbon dioxide tension; Pvo2=central veneous oxygen tension; Met Hb=partial arterial methaemoglobin pressure.
FEV1 (l)1.29 (0.7)1.28 (0.7)1.09 (0.4)1.07 (0.4)0.742
FEV1%FVC (%)45.6 (13.6)46.1 (13.2)44.5 (13.0)45.5 (13.3)0.797
TLC (l)7.0 (1.4)7.0 (1.4)6.2 (2.4)6.7 (1.6)0.836
RV (l)4.2 (1.5)4.3 (1.6)4.2 (1.5)4.4 (1.6)0.797
RV%TLC (%)59.4 (14.8)60.2 (14.0)61.6 (10.1)58.9 (17.9)0.318
Pao2 (kPa)11.4 (4.2)10.6 (1.9)10.5 (1.8)10.1 (1.6)0.739
Paco2 (kPa)7.4 (1.4)6.7 (1.1)7.4 (1.4)6.7 (1.1)0.037
Pvo2 (kPa)5.5 (0.6)5.4 (0.3)5.7 (0.4)5.6 (0.6)0.512
Met Hb (mm Hg)0.4 (0.2)0.5 (0.1)0.4 (0.1)0.5 (0.2)0.614