Determinants of atopic wheeze by allergen exposure derived from logistic regression
| n (%) | Crude OR*(95% CI) | n (%) | Adjusted OR*(95% CI) | p value** | |
|---|---|---|---|---|---|
| *Odds ratios (and 95% confidence intervals). | |||||
| **Likelihood ratio test. | |||||
| Der p 1 exposure | |||||
| Paternal asthma | 76 (13.9) | 2.68 (1.27 to 5.65) | 68 (13.7) | 2.50 (0.98 to 6.40) | 0.060 |
| Maternal asthma | 75 (13.6) | 2.38 (1.11 to 5.10) | 69 (13.9) | 2.41 (1.01 to 5.74) | 0.057 |
| First born | 234 (42.4) | 2.31 (1.18 to 4.51) | 214 (43.2) | 3.00 (1.16 to 7.72) | 0.020 |
| Maternal age | 551 | 1.07 (1.00 to 1.15) | 495 | 1.12 (1.03 to 1.22) | 0.007 |
| Crowding (persons per room) | |||||
| 0.25–0.50 | 100 (18.1) | 1.00 | 89 (18.0) | 1.00 | 0.060 |
| 0.51–0.60 | 132 (23.9) | 0.87 (0.38 to 1.97) | 121 (24.4) | 0.95 (0.35 to 2.60) | |
| 0.61–0.70 | 151 (27.4) | 0.20 (0.06 to 0.64) | 135 (27.3) | 0.23 (0.06 to 0.88) | |
| 0.71–1.66 | 169 (30.6) | 0.41 (0.17 to 1.02) | 150 (30.3) | 0.79 (0.23 to 2.68) | |
| Any smoking at age 1 | 235 (42.6) | 2.04 (1.05 to 3.96) | 197 (39.8) | 3.67 (1.67 to 8.04) | <0.001 |
| Paternal atopy | 207 (41.3) | 2.83 (1.41 to 5.71) | 207 (41.8) | 2.88 (1.26 to 6.13) | 0.011 |
| Quintile of Der p 1 (low) exposure | |||||
| 1 | 109 (20.0) | 1.00 | 97 (19.6) | 1.00 | 0.546 |
| 2 | 109 (20.0) | 1.65 (0.52 to 5.21) | 97 (19.6) | 1.35 (0.37 to 4.88) | |
| 3 | 110 (20.2) | 2.55 (0.87 to 7.49) | 100 (20.2) | 2.44 (0.75 to 7.92) | |
| 4 | 109 (20.0) | 1.21 (0.36 to 4.09) | 100 (20.2) | 1.16 (0.30 to 4.48) | |
| 5 | 109 (20.0) | 1.43 (0.44 to 4.64) | 101 (20.4) | 1.71 (0.47 to 6.23) | |
| Fel d 1 exposure | |||||
| Paternal asthma | 76 (13.9) | 2.68 (1.27 to 5.65) | 68 (13.7) | 2.62 (1.05 to 6.57) | 0.045 |
| First born | 234 (42.4) | 2.31 (1.18 to 4.51) | 215 (43.4) | 3.05 (1.21 to 7.69) | 0.015 |
| Maternal age | 551 | 1.07 (1.00 to 1.15) | 495 | 1.11 (1.02 to 1.20) | 0.012 |
| Maternal asthma | 75 (13.6) | 2.38 (1.11 to 5.10) | 69 (13.9) | 2.43 (1.03 to 5.76) | 0.052 |
| Crowding (persons per room) | |||||
| 0.25–0.50 | 100 (18.1) | 1.00 | 89 (18.0) | 1.00 | 0.026 |
| 0.51–0.60 | 132 (23.9) | 0.87 (0.38 to 1.97) | 122 (24.7) | 1.05 (0.40 to 2.77) | |
| 0.61–0.70 | 151 (27.4) | 0.20 (0.06 to 0.64) | 135 (27.3) | 0.21 (0.05 to 0.78) | |
| 0.71–1.66 | 169 (30.6) | 0.41 (0.17 to 1.02) | 149 (30.1) | 0.74 (0.22 to 2.49) | |
| Anyone smoking at age 1 | 235 (42.6) | 2.04 (1.05 to 3.96) | 198 (40.0) | 3.53 (1.61 to 7.72) | 0.001 |
| Paternal atopy | 207 (41.3) | 2.83 (1.41 to 5.71) | 207 (41.8) | 2.64 (1.18 to 5.92) | 0.017 |
| Quintile of Fel d 1 exposure | |||||
| 1 | 109 (20.0) | 1.00 | 91 (18.4) | 1.00 | 0.688 |
| 2 | 109 (20.0) | 1.55 (0.53 to 4.50) | 101 (20.4) | 1.14 (0.36 to 3.65) | |
| 3 | 110 (20.2) | 1.17 (0.38 to 3.59) | 97 (19.6) | 0.73 (0.21 to 2.47) | |
| 4 | 109 (20.0) | 1.73 (0.61 to 4.95) | 102 (20.6) | 0.88 (0.27 to 2.86) | |
| 5 | 109 (20.0) | 1.18 (0.38 to 3.63) | 104 (21.0) | 0.51 (0.14 to 1.81) | |