Table 2

Effect of exposure to 10 ppm NO2 on incorporation of radioactivity into lamellar bodies of type II pneumocytes

Cellular radioactivity (dpm/mg protein)Radioactivity incorporated into lamellar bodies (% of cellular radioactivity)
−SP-A+SP-A−SP-A+SP-A
Values are mean (SE); n=3-4 experiments.
**p<0.01 between radioactivity from cells of different experimental protocols.
†p<0.05, ††p<0.01 between the percentage of radioactivity in the lamellar bodies from cells of different experimental protocols.
Control33264 (1834)184800 (9482)9.8 (1.2)29.8 (2.1)
3 days121968 (5702)**264264 (12066)**16.3 (2.5)†35.9 (3.6)††
20 days114576 (5948)**260568 (12345)**14.8 (2.1)††34.4 (2.5)†
28 days146916 (6481)**305105 (14193)**16.6 (2.8)††34.9 (2.4)††