Table 4

Significance of correlations between serological parameters and conventional measures of disease severity within individual patients during the entire treatment period

Anti-GM-CSF Ab (μg/ml)SP-A (μg/ml)SP-B (μg/ml)LDH (%ULN)
Nop valueNop valueNop valueNop value
[A–a]Do2=alveolar-arterial oxygen gradient; VC=vital capacity; Tlco=carbon monoxide transfer factor.
p values are calculated from the signed rank test for association within patients (see Appendix).
[A – a]Do2 (mm Hg)98NS1020.054102NS1320.010
Tlco (% predicted)69NS74NS74NS100NS
VC (% predicted)78NS80NS80NS1060.019