Odds ratios (ORs) and confidence intervals (CI) for the risk of asthma with raised CS-IgE levels (logistic regression analysis)
| Age | Strata | Total sample (N) | Cord serum IgE levels | Unadjusted OR(95% CI) | Adjusted† OR(95% CI) | |
|---|---|---|---|---|---|---|
| <0.5 kU/l | ⩾0.5 kU/l | |||||
| % (n/N) | % (n/N) | |||||
| SPT, skin prick test. | ||||||
| *p<0.05. | ||||||
| †Controlling for sex, maternal smoking during pregnancy, age of mother at delivery, maternal and paternal atopy, season of birth, birth weight, neonatal complications, and having a pet at recruitment. | ||||||
| ‡Includes missing observations at ages 4 and 10 as well as negative SPT at one age and missing at the other. | ||||||
| 1–2 | All | 1194 | 10.5% (110/1044) | 8.7% (13/150) | 0.80 (0.44 to 1.47) | 0.72 (0.39 to 1.34) |
| 4 | All | 1068 | 15.2% (141/928) | 15.0% (21/140) | 0.98 (0.60 to 1.62) | 0.92 (0.55 to 1.52) |
| Positive SPT | 175 | 30.8% (12/39) | 38.5% (52/136) | 0.71 (0.33 to 1.52) | 0.60 (0.27 to 1.36) | |
| Negative SPT | 688 | 10.7% (8/75) | 11.9% (73/613) | 0.88 (0.41 to 1.92) | 0.90 (0.41 to 1.97) | |
| No SPT conducted | 205 | 8.9% (16/179) | 3.8% (1/26) | 0.41 (0.05 to 3.21) | 0.54 (0.11 to 2.60) | |
| 10 | All | 1191 | 11.9% (124/1040) | 18.5% (28/151) | 1.68 (1.07 to 2.64)* | 1.66 (1.05 to 2.62)* |
| Positive SPT | 288 | 27.5% (14/51) | 30.5% (72/237) | 0.86 (0.44 to 1.69) | 0.83 (0.41 to 1.67) | |
| Negative SPT | 485 | 16.3% (8/49) | 5.5% (24/436) | 3.81 (1.54 to 9.39)* | 3.35 (1.41 to 7.93)* | |
| Incomplete SPT information‡ | 418 | 7.6% (28/367) | 11.8% (6/51) | 1.56 (0.49 to 4.93) | 1.77 (0.52 to 6.07) | |