Odds ratios (ORs) and confidence intervals (CI) for the risk of sensitisation with raised CS-IgE levels (logistic regression analysis)
| Age | Skin prick test | Total sample (N) | Cord serum IgE levels | Unadjusted OR(95% CI) | Adjusted† OR(95% CI) | |
|---|---|---|---|---|---|---|
| <0.5 kU/l | ⩾0.5 kU/l | |||||
| % (n/N) | % (n/N) | |||||
| *p<0.05. | ||||||
| †Controlling for sex, maternal smoking during pregnancy, age of mother at delivery, maternal and paternal atopy, season of birth, birth weight, neonatal complications, and having a pet at recruitment. | ||||||
| 4 years | Any | 862 | 18.1% (135/748) | 34.2% (39/114) | 2.36 (1.54 to 3.63)* | 2.29 (1.47 to 3.57)* |
| House dust mite | 11.8% (85/748) | 16.7% (19/114) | 1.56 (0.91 to 2.68) | 1.47 (0.85 to 2.57) | ||
| Grass pollen | 7.1% (53/748) | 14.9% (17/114) | 2.30 (1.28 to 4.13) | 2.29 (1.25 to 4.19) | ||
| Cat | 4.8% (36/748) | 14.0% (16/114) | 3.23 (1.73 to 6.04) | 3.19 (1.67 to 6.08) | ||
| Dog | 2.1% (16/748) | 5.3% (6/114) | 2.54 (0.97 to 6.64) | 2.34 (0.85 to 6.43) | ||
| Alternaria | 4.0% (30/748) | 12.3% (14/114) | 3.35 (1.72 to 6.53) | 3.18 (1.59 to 6.35) | ||
| Cladosporium | 2.1% (16/748) | 3.5% (4/114) | 1.66 (0.55 to 5.07) | 1.79 (0.55 to 5.86) | ||
| 10 years | Any | 900 | 25.3% (200/789) | 38.7% (43/111) | 1.86 (1.23 to 2.82)* | 1.73 (1.13 to 2.65)* |
| House dust mite | 18.6% (147/789) | 26.1% (29/111) | 1.55 (0.98 to 2.45) | 1.42 (0.89 to 2.28) | ||
| Grass pollen | 11.7% (92/789) | 23.4% (26/111) | 2.77 (1.66 to 4.63) | 2.20 (1.32 to 3.67) | ||
| Cat | 7.7% (61/789) | 9.9% (11/111) | 1.31 (0.67 to 2.58) | 1.14 (0.56 to 2.32) | ||
| Dog | 3.5% (28/789) | 8.1% (9/111) | 2.40 (1.10 to 5.23) | 2.19 (0.97 to 4.95) | ||
| Alternaria | 1.9% (15/789) | 2.7% (3/111) | 1.43 (0.41 to 5.03) | 1.22 (0.33 to 4.51) | ||
| Cladosporium | 1.3% (10/789) | 0.0% (0/111) | Cannot be calculated | |||