Association of CYP2A6 genotype with LAA score, %Kco, and %FEV1.0
| n | Age | CC | %D | |
|---|---|---|---|---|
| LAA=low attenuation area score; Kco=carbon monoxide transfer coefficient; FEV1.0=forced expiratory volume in 1 second; CC=lifelong cigarette consumption (pack years); %D=percentage of subjects with genotype D. | ||||
| **χ2=7.8, p=0.005 v LAA <8.0. | ||||
| †χ2=4.9, p=0.03 v %Kco ≥65. | ||||
| ‡p<0.01, ‡‡<0.05 v %Kco ≥65. | ||||
| §p<0.01, §§p<0.05 v %FEV1.0 ≥50. | ||||
| ¶p<0.01 v LAA <8.0. | ||||
| LAA score | ||||
| <8.0 | 127 | 65 (9) | 59 (32) | 37.0 |
| ≥8.0 | 76 | 69 (9)¶ | 66 (34) | 18.4** |
| %Kco | ||||
| ≥65 | 115 | 65 (9) | 59 (29) | 34.8 |
| <65 | 55 | 71 (8)‡ | 70 (39)‡‡ | 18.2† |
| %FEV1.0 | ||||
| ≥50 | 146 | 65 (10) | 59 (31) | 32.2 |
| <50 | 57 | 71 (8)§ | 69 (38)§§ | 24.6 |