Table 3

Annual rate of decline in post-bronchodilator FEV1 by treatment allocation

StudyAnnual change in FEV1 (ml/year)Reduction in annual change in FEV1 (ml/year)
PlaceboSteroid
All data mean (SE) except where SE not reported or calculable (*) or where median values reported (†, see text)
NR=not reported; FEV1 =forced expiratory volume in 1 second.
Burge et al7−59 (4.4)−50 (4.1)9.0 (6.0)
Lung Health Study Research Group5−47.0 (3.0)−44.2 (2.9)2.8 (4.2)
Pauwels et al10−60†−46.7†13.3 (6.8)†
van Grunsven et al19NRNR39.0 (23.0)
Vestbo et al12−49.1*−46.0*3.1 (8.1)
Weir et al9−56.9 (15)−20.6 (16)36.3 (22.3)