Relationship between BMI and spirometric parameters and airway responsiveness*
| Overall | Boys | Girls | ||||
|---|---|---|---|---|---|---|
| Outcome | β (95% CI) | p value | β (95% CI) | p value | β (95% CI) | p value |
| *Adjusted for age, race, sex, clinic, Tanner stage, and parental smoking. | ||||||
| †Also adjusted for height. | ||||||
| ‡Bronchodilator (BD) change defined as change in FEV1 with bronchodilator divided by initial FEV1. | ||||||
| Post-BD | ||||||
| FEV1 (l)† | 0.006 (0.001 to 0.010) | 0.01 | 0.003 (−0.003 to 0.009) | 0.32 | 0.008 (0.004 to 0.012) | 0.02 |
| FVC (l)† | 0.012 (0.007 to 0.017) | 0.0001 | 0.009 (0.002 to 0.016) | 0.009 | 0.014 (0.006 to 0.021) | 0.0004 |
| FEV1/FVC | −0.242 (−0.118 to −0.366) | 0.0001 | −0.297 (−0.127 to −0.467) | 0.0006 | −0.188 (−0.001 to −0.375) | 0.05 |
| Peak flow (l/min)† | 0.230 (−0.674 to 1.14) | 0.61 | 0.149 (−1.127 to 1.425) | 0.82 | 0.640 (−0.717 to 1.987) | 0.36 |
| BD change‡ | −0.003 (−0.001 to −0.004) | 0.02 | −0.001 (−0.004 to 0.002) | 0.37 | −0.003 (−0.001 to −0.006) | 0.02 |
| Log PC20 | 0.034 (0.012 to 0.057) | 0.003 | 0.021 (−0.008 to 0.054) | 0.18 | 0.043 (0.008 to 0.078) | 0.02 |