Odds ratios (OR) and 95% confidence intervals (95% CI) of multiple logistic regression analyses on irreversible airway obstruction (FEV1 prebronchodilator <80% predicted and FEV1 reversibility <9% predicted at visit 2, only patients with prebronchodilator FEV1 <80% predicted included) and on a reduced postbronchodilator transfer coefficient ( kco, <80% predicted, all patients included)
| Irreversible airway obstruction (n=130) | Reduced postbronchodilator Kco (n=162) | |||
|---|---|---|---|---|
| Outcome (no of cases in analysis) | OR | 95% CI | OR | 95% CI |
| Age at visit 2 | 0.96 | 0.91 to 1.02 | 1.01 | 0.95 to 1.07 |
| Male sex | 0.88 | 0.33 to 2.32 | 0.33 | 0.14 to 0.80 |
| Pack years at visit 2 | 1.01 | 0.98 to 1.04 | 1.04 | 1.01 to 1.07 |
| FEV1 pre-bd at visit 1 (% pred) | 0.95 | 0.92 to 0.98 | 1.00 | 0.98 to 1.03 |
| ln(slope BHR) at visit 1 | 0.64 | 0.41 to 1.00 | 1.03 | 0.69 to 1.53 |
| Reversibility at visit 1 (% pred) | 0.96 | 0.91 to 1.00 | 1.00 | 0.97 to 1.04 |
| Allergy at visit 1 | 0.63 | 0.12 to 3.38 | 2.29 | 0.38 to 13.72 |
| Untreated period | 1.05 | 1.00 to 1.10 | 0.98 | 0.94 to 1.03 |
| Use of steroids at visit 2 | 0.22 | 0.07 to 0.64 | 2.03 | 0.86 to 4.81 |