Effect of treatment on lung function tests, Pao2, BAL fluid and plasma variables in patients with DPB
| Before treatment | After treatment | p value | |
|---|---|---|---|
| %VC (%) | 77.4 (7.4) | 94.0 (5.2) | <0.005 |
| FEV1% (%) | 64.7 (3.0) | 68.8 (2.2) | NS |
| FEV1 (l) | 1.58 (0.25) | 1.96 (0.23) | <0.005 |
| Pao2 (kPa) | 9.7 (0.4) | 10.4 (0.3) | <0.05 |
| BAL fluid | |||
| Total cells (×105/ml) | 5.2 (2.1) | 1.0 (0.2) | <0.05 |
| Neutrophils (×103/ml) | 298.2 (126.1) | 15.3 (10.6) | <0.05 |
| Lymphocytes (×103/ml) | 65.4 (15.4) | 8.2 (2.9) | <0.05 |
| HBD-1 (pg/ml) | 191.1 (76.9) | 268.6 (114.1) | NS |
| HBD-2 (pg/ml) | 42.2 (18.6) | 7.1 (3.6) | <0.05 |
| Plasma | |||
| HBD-1 (pg/ml) | 6,763 (825) | 6,835 (666) | NS |
| HBD-2 (pg/ml) | 175.0 (18.1) | 161.0 (26.5) | NS |
| Data are mean (SE). | |||
| VC=vital capacity; FEV1=forced expiratory volume in 1 second; Pao2=arterial oxygen tension. | |||